Owning both (actually down to one #1 and 3 BLR's), I find that when I head out to hunt or just knock around the brush, a BLR seems to come to hand much more often. Being basically carbines, the BLR's are easier to handle, whether horseback or getting in and out of a truck, a little easier to carry one handed and snap to the shoulder without thinking. Accuracy has never been a problem. My last #1 is not for sale, but the BLR's just seem to be ready to go anytime, like a good dog. About that .243, in my area, we've found bullet performance on deer to be more than a little inconsistant, whether factory or handloads. One round will give fine performance then the next will either fragment or pencil through. Haven't seen that problem with anything else I can think of. Even a 250 seems to be more reliable. Just to be safe, you ought to get a 22-250 and a 7-08, 308 or 358. Then you're covered