H110 and WW296 usually have a very narrow range of quantity used. If you go over it, boom. If you go under it, I don't know what happens but reducing the recommended load is taboo.
I have 8 pounds plus of H110 that I wish I could use with some cast bullets that are gas checked or otherwise.
My experience with either gas checked or plain base bullets, the H110 will cause barrel leading at the throat in my 357 contender barrels.
There are too many more flexible and forgiving powders for magnums shooting cast bullets like, 2400, 4227 and so on.
I shot a ton of lead through 44 Specials and Magnums and I nearly always ended up using H4227 or IMR 4227.
Harold Clark