I have a 10" 45 Win Mag and love it. It does kick a bit at full strength loads. I load full 230 gr. for hunting. Some downloaded 185 for practice and some 45ACP loads (in a 45 Mag case) for plinking (very mild). I have heard that some shoot 45ACP ammo in the barrell. I haven't tried that. I put fiber a sight from Ed on the rear and gunsmithed in a fiber front sight.
good luck