Conditions do affect results, depending on the chrony and the angle at which you were shooting. If, for example, the first session was shot with the gun level and the second session had the gun pointing up or down several degrees, that could make a difference. Also, some powders are sensitive to humidity and cases loaded in dry conditions can have a different velocity than cases loaded in humid conditions. Also, if you used cases from a different lot, or a different lot of primers, that could do it too.