I`m not trying to rain on your parade, but I think that the .480 was a big step sideways. It will really do nothing more than the .454. It is way more than you need for deer also. I have an Encore in .357 max. which will shoot farther and hit pleanty hard enough for deer, plus it has far less recoil. It has a 15 in. Bullberry barrel and shoots sub. moa. For hunting I would recomand a fixed 2X scope. If you want more for range shooting or varmint hunting go with a 1 x 4X scope. Handgun scope have a very small field of viesion and eye relief is very critical. The only time I will carry a scoped handgun is when I`m setting a stand, if walking or driveing I carry an iron sighted revolver.
There is nothing wrong with a .480, in fact it is a very good round. It will do the job on deer, and I have been known to carry a .454 revolver which is just as much over kill as the .480. It`s just that the .480 would be better on bear, or moose, ect.
What the heck, get the .480 and a .357 max., that will pretty well cover your big game hunting. Then you can get .204 Ruger and a .22RF and have your varmint and small game covered too.