The Vaquero is just as strong as the Black Hawk. May I suggest if you are going to hunt, go with the Black Hawk as it has adjustable sights. Point of impact for a plinker load is not usually the same as for a hunting load and the BH will give you the flexibility of adjusting your sights for either load. Of the two calibers, 44 Mag or 45 Colt, either is fine for hunting. If you don't reload, I suggest the 44. Not saying factory 45 Colt loads can't take a close in deer, but with factory loads, you loose about 15,000 PSI of potential pressure compared to judicious handloads