My gun seems to like 50 caliber Winchester X-150 seems to like 245 grain Powerbelt HPs and 100 grains of Triple Seven. My best group with this load is 1.25" at 100 yards. It also shoots T/C 240gr Sabots good. How would these perform on Deer?
I think you will really like the performance of either of these two bullets on deer. The "cheap shot" as somebody already said is an ugly bullet but it works great.
I myself use a 300 grain bullet with a Nosler sabot with the same powder charge. I do use loose powder vs pellets, 100 grains of loose is a little more power than 2-50 grain pellets. I shoot Hornady XTP's for recreation and target practice (saving on expense) and then switch to Nosler partitions for hunting. The guaranteed penetration, the hydraulic effect on tissue, and the cutting of copper make it very thorough when harvesting an animal.
Here is another option you might want to try. I am having very good success with .458 (45/70) bullets in an Orange MMP sabot. These are real rifle bullets and closer to the bore size. Again Nosler's for hunting and Hornady's for target practice. The Nosler's actually shoot a little tighter than the Hornady's from my A&H and a Remington.