This is kind of a rhetorical question. I have successfully drawn a mule deer tag for West River in South Dakota. My .30-06 will go along, but I'd like to take one with my .454 Casull, TC Encore-12" barrel. I shot a pair of whitetails with it last year, but shooting them from a tree stand was almost cheating! I have a 320 gr. load with 27 gr. H110 and a 355 gr. load with 27 gr. H110, both hard cast gas-checked. With the same sight setting I can hit milk jugs everytime from a Creedmore position, and oil bottles most of the time at 100 yds. with either load, I use a Leupold 4x scope. Any pros or cons to either load? I know they'll both kill a mule deer, my favorite mule deer gun is my mother's .243 with 100 gr. Nosler Partitions, it's never let me down, but she's also drew a tag this fall. I know either load has enough juice, let me know what you guys think.
Selmer