Rugers are the only multi purpose hand guns when it comes to CAS and hunting,IMHO.
I like the .45lc, but I reload. The load I use (which is on the Hodgdon website), a 300 gr. xtp jhp, with 21 gr of Lil Gun, will take down Mule deer, whitetail, and any hog you run across. At a reasonable distance of course.