I read an article in a Predator Extreme magazine that you might be interested in. If you want to keep the pelts from your varmints, Environ-Metal, Inc. (Hevi-Shot) has developed a new bullet. It's a Hevi-Shot Dead Coyote Varmint Bullet. The .224 bullet weighs 70 grains, but because its density is heavier than lead, it is shorter than most 60 grain bullets. That means it can be shot in slower twist barrels like 1:12. The bullets are hollow point designs with jackets optimized to burst upon penetration. The factory claims another special point about these bullets. They have zero retained weight. That will give you a small entry wound, destruction of vitals, and no exit wound. I don't believe they make finished ammo, only the .224 bullets, with .308 bullets on the design board. Both the .223 Remington and the 22-250 could be loaded with these.
I shoot a .223 Remington with either Hornady V-Max 40 grain moly, or Black Hills 40 grain hollow point moly rounds. Out to about 200 yards, either round passed through the coyotes I've shot broadside. On a front-quartering shot, there was no exit wound. 200 yards is about my maximum range with these lighter bullets. I just received boxes of both above named rounds in 55 grains. I'll now see how they compare.
TennSquire