Setting up the Dillon 550 for several different round can vary in price quite abit depending on the rounds you chose. For the .222, .223 and the .222 mag. you can use the same cartridge converstion includeing powder funnel. In fact you need only 1 cartridge conevesion for all rounds that have the same size casr head. ie. If you get a cartridge conversion for a .30-06 it will work with the .243, .257, .270 .308, .22-250, .35 Whelen ect. You will need to buy a powder funnel for each different cal. and if the rounds are of the same cal. but one is real long and the other very short you may need 2 different lenths of powder funnels for the same cal. You only need 1 tool head if you want to change your dies all the time, but everyone I know get a seperate tool head and powder die for each round they load, this way you never have to set your dies but once. I have well over $1000 invested in my 550, but I load for 6 different wildcat rounds and most common factory rounds, in rifle, plus I load several different handgun rounds. Some rounds I have 2 different tool heads for. 1 set-up for FL resizeing and 1 for neck size only. I also have extra powder measures. I got my Dillon in the late 1970`s and have been adding thing ever since. Once you load on one you`ll never want anything else. :wink: