I am about to do some cast bullet loading of the 25-35 myself and I'll quote Lyman's 42nd edition which lists the 110 grain bullet (257325) but none larger. The powders listed for the 110 grain bullet are as follows; 5 grains of Unique @ 1170 fps, 7 grains of 2400 @ 1160 fps, 8 grains of 4227 @ 1200 fps, 15 grains of 4198 @ 1880 fps, 10 grains of 4227 @ 1500 fps, 13.4 grains of 2400 @ 1920 fps.....hope this helps. Again, this is straight out of the Lyman 42nd reloading manual.