brian:
I own several Rugers and a 22A...and each serves a different purpose.
All of my .22 handguns are a lot of fun to shoot although the Rugers tend to be more reliable and less picky about ammo...especially picnic shells if your planning to roll tin cans. Rugers are also more accurate IMHO.
My 22A seems to like low-velocity (Wolfe and Rem SubSonics) ammo best which tends to get a bit pricy for plinking, but it is a bit lighter than the Rugers and I tend to shoot it longer as a result. The 22A is not as accurate in my hands...and it requires more TLC (cleaning/lubrication).
Walthers and Neos...don't own any but I've handled them a few times in the gun shop. Got the urge to buy a Neo a while back but most of the reviews/commentary on this board and in the mags was less than stellar...so I bought a .357 instead :lol:.
Anyway, let us know what you end up with and how you like it.
Good Luck and Be Safe! ...Chris