You are better off with the 308 for a wider field of use. It has some great bullets for hunting with a hand gun. I have dispatched many deer, hogs, one buffalo, and one Moose with this round in a Competitor Pistol. The factory 150 gr does well on just about anything from elk down , if you use a good quality bullet on the big stuff. I reload for it and use the Hornady 130 gr SSP pistol and the Nosler 125 gr Ballistic tip for deer behind 50 gr of Varget. The 130 Gr ssp or 150 gr Boat tail of various makes behind 46.5 gr of Varget ,Hornady and Serria prefered, for deer, hogs, Up through Carabou. 150 and 165 Gr Hornady or partitions for the Buffalo and Moose ( 46 gr of W 748 in the 165). My gun gets 2900 from the 125 and 130 gr, 2700 from the 150, and 2600 from the 165 in its 18 in barrel. in the 14 in barrel about 200 fps drop has occured so I do not go any heavier than the 150 for it. all loads use WW brass and WW standard primers. Remember always start 10% reduced loads and work up. However the factory loads work well also if you want to go that way. My hunting buddy uses an Encore in this caliber and has taken everything I have with factory loads in his 15 in pistol With the 150 gr Interbond, interlock or the partition of the same weight.
Hope this helps
fennell :-)