I took my .375 Contender 21" carbine out yesterday, mainly to chrono some loads I'd worked up with Reloader 7 behind 200gr Sierra FN bullets. The gun turned out to be fairly accurate with all loads, averaging less than 2" with everything I tried. Actually, 35gr of Re 7 averaged around 1" and 2000+ fps. I went all the way to the max load of 38.5gr, which gave me around 2" and 2200fps and zero signs of excessive pressure. I'm positive the load was more accurate than that, but I the recoil had started getting to me just a bit. The .375 is a pretty stout round in a 5.5lb gun, so I really can't imagine what it would be like in a 14" pistol!
Next, I plan on trying a 235gr Hornady, so wish my shoulder luck!