I realize 1 deer doesn't mean everything. The one I shot was at 40 yards, the bullet slipped between the ribs going in and out. There were 2 bucks and off they ran. I could make a deer out through the trees at about 90 yards, just standing there and flicking it's tail. I assumed it was the other buck. I looked through my bino's and I could see a bullet hole behind the shoulder (this would be the off side). I couldn't get a clear shot, and I didn't want to move closer in fear of spooking him.
Obviously the shot had been placed well, so I waited. In about 3-4 minutes the deer dropped, tried to lift his head and expired. When I dressed him, the lungs were in fine shape except for a .358 caliber hole through both of them. The exit hole was barely bigger then the entrance, if the bullet expanded you can't prove it by me.
I believe they will work fine for bigger game or make sure you nail the shoulder going in, but apparently going through the lungs of a 125 pound deer at 40 yards didn't offer enough resistance for any type of expansion.
For what it is worth I have had VERY good luck with Nosler Partitions on deer in that caliber, both the 225's and 250's. Just thought I would try some of the 220's out for giggles.