Had it happen once on my 12 inch 44 mag. Was shooting single holes at 50 yards up to the moment it wasn't. Started looking for looseness and found the TC DuoRing base had loosened from the barrel. Reset it with more thread lock and haven't had the trouble since. Suspect it will come some day.
Now every once in a while, I slap the side of the barrel with my open hand and listen/feel for vibrations , which would indicate something was loosening. That's how I found the loose base the first time. When you hit it, just see if anything vibrates--if it does, start looking for what it is!
Mike