Tom-
The easiest, quick and dirty method that doesn't need specialized equipment is to use a dial caliper to measure from the outside edges of the two bullet holes farthest apart, and then subtract one bullet diameter, which will give you the center to center spread.
Let's say you shoot a five shot group at 100 yards with your .308. Your calipers tell you the two bullet holes farthest apart are .986. .986-.308=.678 group size.