I really like the 6.5's but don't see them as preditor rifles. I think realisticly you pass over that at 25 cal. You can of course shoot graydiggers with a 458 win mag but unless you just like the extra recoil, what's the point? In my 6.5's, two, I also like the 129gr Hornady and the 140gr Hornady. They will both kill a coyote very dead.