Good points Crayfish, I forgot to mention that I started with 150 gr. bullets the first time I went to group my .30-06, and no matter the brand, that featherweight barrel hated them, so then I moved up to 165 gr. BT's, I never ended up having to switch powder, but that's sometimes necessary as well. We shoot .30-06, .243, and .308 mainly, with a little .30-30 and load 7 mm mag and .338/.378 Wby. for a friend, so for our main loading stock of powder we have IMR 4350, IMR4831, and H380. We like to use as few different powders as possible so we can keep costs down and these three serve us very well. We use slow mag powders for the Wby., in case you were wondering.
Selmer