Moose, Mine is a 14" 45LC/.410. I get very good accuracy from the heavier slugs..260-300 Grainers,with stout loads. So so accuracy from 250 on down.Might want to go to even heavier just to see how they shoot. I think the part that facinated me so was the 250 Barnes point of impact was perfect for a reddot sighted in with 300 XTP's! Its a handy chambering and I hope to never be without one.
I have a Bisley Black Hawk in 45 LC that likes the heavies also,but does better with the lighter ones than does the T/C.