Stock that fits you, double ear protection at the range (plugs and muffs), good sandbagged bench and proper technique, Limbsaver pad, 7mm-08, magnum recoil shoulder pad. In the field, raise your right elbow (or left, if it's your trigger hand).
I don't shoot the really big stuff but do shoot 270, 30-06, 300 Win, 8mm Rem, 350 Rem, 35 Whelen, & 45-70 fairly regularly with pretty decent handloads (and less frequently a 375 H&H and 3 1/2" 12 ga. turkey loads in an 870; the 870 probably kicks more than anything!). The above list helps me keep from flinching too badly. And I think they're an aid to my accuracy even with rifles that don't kick noticably (243, 257 Rbts, 7mm-08, etc).
Good luck. -WSJ