In fair weather season I go to the outdoor range, in the middle of the week, there is rarely anyone there at this range, have the place to myself.
I then practice moving a lot, shooting from all different positions and from behind things, laying down, and sometimes I run fast for short sprints before engaging the targets. Also practice presentation from my carry holster a lot. If i'm going to carry, I'd better be smooth about presenting it if I have to.
Of course the reason I go to the range alone is because I don't want other people there when I practice this way, I need space so to speak, among other obvious reasons. (What the h*ll is he doing??) Although I know most all of you would understand I'm sure.
OH....if ya practice like this by yourself, be REAL safe while on the move with your weapon, and preenting it...there is no one there to take you to the hospital if your unsafe while playing combat by yourself.
I think the best drill is practicing drawing your weapon and firing it, and making your movements smooth and safe.
Plinking with a few hundred rounds is great for trigger control and good practice all around.
50 rounds of intense concentration presenting your weapon and shooting from odd positions could save your life in a pinch.