:cb2: I have one ported gun, a .357 Colt Grizzly. You can really tell the difference when shooting heavy loads through it and some of my other 357s. However, it was one of the first handguns I ever bought, and it only came ported. Couldn't afford a Python, so I at least got the Python barrel. The ported part could have been left off. You don't really need a ported barrel in the calibers you mentioned: .45, .44, and .41. The largest I have fired have been the .475 and .454, and didn't think they needed a ported barrel either. It's not like you're gonna be double tapping deer. Unless of course, the deer is carrying a bigger gun than the one you've got!