Might as well get my opinions in here too. I load .45 Colt and .357 Mag with both H110 and Lil'Gun, now going almost exclusively with Lil'Gun. In the longer barrel Rugers, 7 1/2", the two seem to perform almost the same, with Lil'Gun getting the nod, slightly. As JohnK notes, less powder for essentially the same velocity. In my short, 4 5/8", Rugers, Lil'Gun gives a better velocity - less dropoff from the longer barrel that H110. Lil'Gun also appears to produce less flash in low light. I haven't tried the lighter .357 bullets with it yet - I'm still stuck on HS6 for a lot of loads.