MH Wash
Have seen numerous 'yotes taken with all sorts of handguns and bullets. By far the quickest kills most always are from the light for cartridge, fast stepping, jacketed HPs. In the .357 factory Fed or Win 125 HPs are excellent performers. These loads can be duplicated with any of the 125 HPs. I was using Win 125 HPs for reloading but have seen what the Speer Gold Dots can do on 'yotes out of the .357, I will use them next. In .41 you just have a hard time beating the 170 gr Sierra HC. You should get 1400+ fps with your short barrel and they work quite well in that range. I was getting 1480 fps with a healthy dose of H110 in a 4" S&W.
All 'yotes are pretty tenacious and sometimes don't want to give up the ghost very quickly. I have seen and shot several with SWCs at magnum velocities with both of these cartridges and they will kill 'yotes. While some died quickly others took some tracking, even thoght solidly hit, and one was not found. However, with the HPs I never saw one go very far with a good hit, not near as far as with the SWCs, and never lost one. If a shot at a 'yote presented itself and I only had the SWCs in the revolver I would take the shot as they will do the job. But if hunting 'yotes I would stoke up with the light weight, fast stepping HPs.
Larry Gibson