-all around cartridge from deer to bear, moose and beyond
Its hard to argue with a .45-70 when the game gets big and bitey. 350g for antlers, 540g hardcast for bitey.
-best long range cartridge
The .307 pushing a 170g Speer to 2535fps wins this race: 1,000fpe out to 370 yards, down 24.7. The .356 Win pushing a 180g Speer isnt far behind at 350 yards, down 20.
-hardest hitting
Thats easy, the .45-70 pushing a 350g to 2183fps. Over 3700fpe at the muzzle, about 850fpe more than the .356Win or .444, the runners up. North Fork bonded, in my case.
-flattest shooting
At -10 its the 7mm STE pushing a 139g Hornady to 2710fps, 305 yards. The .307 and .357Win are a hair behind at 300 yards.
The above are based on the assumption that all loads are zeroed for Maximum Point Blank Range for a 6 diameter target.
7-30 Waters, 139g Hornady @ 2600fps, 2086fpe @ muzzle, 207yd zero, 242yd MPBR
7mm STE, 139g Hornady @ 2710fps, 2266fpe @ muzzle, 215yd zero, 222yd MPBR
.30-30, 170g Speer @ 2300fps, 1977fpe @ muzzle, 190yd zero, 222yd MPBR
.307Win, 170g Speer @ 2535fps, 2426fpe @ muzzle, 207yd zero, 244yd MPBR
.356Win, 180g Speer, 2654fps, 2815 @ muzzle, 211yd zero, 247yd MPBR
.356Win, 220Speer, 2344fps, 2684fpe @ muzzle, 195yd zero, 228yd MPBR
.375Win, 220g Hornady, 2275ps, 2661fpe @ muzzle, 179yd zero, 209yd MPBR
.444 265g Hornady @ 2200fps, 2848fpe @ muzzle, 172yd zero, 201yd MPBR
.45-70, 350g North Fork, 2183fps, 3703fpe @ muzzle, 174yd zero, 204yd MPBR
What hasnt been taken into consideration in the above, however, is bullet construction. Pretty slim pickings for 7mm bullets for tube mags and things are no better for the .375. For the .45-70 you can choose from a 250g and 300g Barnes X, a 300g Speer Uni-Cor or Nosler Partition, or 350g A-Frame or North Fork bonded-core bullets. Of course with the .45-70 you can go hardcast and go really heavy, with 540g Garrett Hammerheads.
The fact is there is no best it all depends on what you will be hunting, how much recoil you want to put up with, and myriad of other factors. I shoot a .44 Mag Browning B92 and Marlins in .30-30, .375Win and .45-70. If I had to pick one to hunt with the rest of my life it would be the .45-70.