teddy, let us know how these work out for you. Over the years, I have shot a bunch of elk with std. bullets in 165 and 150 out of a .300, but if I were hunting out of state or going for big bulls, I would use Nosler Part. The other bullets of this type will be fine, I just like Noslers. Now after all these years, I am leaning more and more to heavier bullets. I loaded 50 200 grain Nosler Part. for elk, moose, etc. A bad angle, or quartering shot the heavier bullet will penetrate a bit farther all else being equal. It just seems to me, and this is just an observation on my part, that a heavier bullet on the " average" drops game a little quicker.
I have dropped elk in their tracks with a 150 gr. Nosler BTBT, but it was a perfect broadside shot. And I was hunting cows in an area where they were thick. So I could have waited if need be. I think you 150's will be fine, but for my use, I am leaning to at least a 180.