Here in coastal Alaska, the deer are small but large brown bears sometimes come at the shot to take the gut pile (and more if they can). Only a couple years ago the paper reported on a local guy who thought the bears had gone in so he took a deer with his .243. A bear picked him up and shook him before it took his deer. I knew a fellow who hunted here for 40 years with a M70 in 375 H&H and 100 new brass. He arrived here after Normandy, Battle of the Bulge, etc. and then using the GI Bill to obtain a BS in Forestry. He took most every kind of game with that 375 and claimed those 100 cases were still holding up over 40 years later. He was also a part-time gunsmith and that is how I got to know him.