Windcutter--The 1-18 twist is the way to go in a 45. I have a 45-90 in 1-20, and a couple in 1-18. Beyond 800 yards the 1-18 consistently groups noticeably better than the 1-20. Out to 600 yards the difference is there, but it doesn't seem to be as pronounced.
Rechambering an existing 1-18 to a longer cartridge is the easiest route to take. Shoot straight, rdnck.