I prefer the pass thru shot. Two reasons. I like two holes providing a blood trail. Secondly, and more importantnly in my book, I don't like to shoot game in the meatest portions. I would rather trim around holes thru the ribs than toss most of a shoulder filled with blood shot meat. Admittedly, the problem of blood shot meat not as bad at handgun velocities, byt why risk it at all. There is a reason God put the vitals in the middle, to give the biggest target and margin for error. My 2 cents, others may vary.
Good luck on the hunt. I will be out on 11/4 for cow elk with a 358 jdj.