So far my best loads have been using H-4198 and Hornady V-Max bullets in 50gr and 55gr, I am using R-P cases with CCI BR-4 primers. I won't tell you how much powder because your handi might not be just like mine, but give it a whirl, it shoots good for me, 1/2 moa at 100 yards and right at 1 moa at 300 yards!
Greg