I have shot several deer with the 230 grain Hydra-shok, that had been hit by a vehicle or somehow injured and they have done well, the majority were headshots however so that is really not the best sample. However the ones that I have body shot expired quickly and injured/wounded deer can be pretty tough to kill. But I have shot several wild hogs with the load and it has done fine. The 45 a.c.p. would not be my first choice for deer hunting but under the conditions that you described, under 25 yards and a carefully picked shot it would work. Remember a lot of people bet their lives on the 45 a.c.p. stopping a 200 lbs plus person intent on killing them, it certainly should be adequate for a 125 lb deer under similar circumstances. Check your local laws on the bullet selection though because where I live the double tap round you discussed would not be legal due to being a full metal jacket, you would need to use a cast bullet, soft point, or hollow point. good luck on your hunt