Welcome aboard! The syn stock set weighs 5oz less than the wood set. The wood stocked rifle is a little easier to make changes to the forend for accuracy improvements if needed, the syn forend is hollow and there's no removable spacer. Other than those issues, take your pick, the wood stocked rifle usually sells for a little less, but that can vary.
The .280 is one of the best shooting calibers from H&R, you should enjoy it a lot!!
Tim