To add to what Lloyd was saying, the situation has a huge implication on the out come. Here in Colorado I hunt elk mostly and the killing area on a bull is pretty big, but the toughness of the animal make it more critical to shoot it perfectly. I like the paper plate rule, in that you can shoot to the distance that you can keep ALL OF YOUR SHOT ON ALL OF THE TIME. On a good day I can stand and shoot off hand at 100 yards and manage it, on a good day. This is not a shot I would try in the field unless the animal was already wounded. For me 50 yards offhand is my limit and prefer much closer, if I have a good rest then I could stretch that out to 80 yards or so. No harm in carrying a range finder too if it helps judge distance. And of course when you are in the hunt if you doubt the shot for a split second, get closer.
Also not to be mean, my background is rifle shooting before picking up handguns again seriously 5 years ago, great rifle shooting means little to great pistol shooting. I know a gentleman that is one of the best rifle shooters in the world, has the titles and trophies to prove it. But couldn't hit a 5 gallon barrel at 25 yards on a dare! Rifles will teach trigger control, sights, and such but if you go into it with a ego, handguns will kick your butt and frustrate you. I know, it is exactly the pitfall I fell in. Start slow, read basic books because you need to relearn from the beginning and things will go quicker in your growth process. My thickheaded ways made me fight simple things for so long and not learn basic stuff that once was applied made a world of difference. Things like gripping the gun EXACTLY the same every time from every position is critical. Something that you can fudge with rifle and get away with, but not handguns.
I say this just to save you a lot of headaches that I put myself through.