Obviously, it depends on what you are hunting. Most fellas want elephant blackpowder guns for white taill. NEF about has the corner on the market for hammered single barrels. I have an old H&R Shikari in 45-70 with the brass cleaning rod. It is one heck of a "trunk gun." (keep it in the trunk for those unexpected opportunities to hunt or shoot.) Smokeless or black powder works fine in it. The sights aren't really for long range sighting. They are much too wide for fine target sighting, but for drawing down on a white tail at 100, the sights are just right. It has done in wood chucks, deer, roaming dogs, a few cats, and even a wayward bull. It has come in handy to dispatch animals injured on the road etc.
Years back a friend had an H&R in .357 Maximum. Right handy little gun also, and the cartridge did right well on deer.