I used a 7TCU in my Contender pistol in IHMSA competition and got to like the cartridge alot. So I got a custom 23" rifle barrel and stocks and made a rifle out of it. This rifle is so sweet, super light and so much fun to shoot.
I tried different bullet weights in IHMSA and found, to my surprise, that the 140 Sierras shot flatter than lighter bullet weights, also Sierras. It must have to do with the 140s having a higher ballistic coefficient or possibly it was a more efficient load combination.
In Sierras manual, they advise against using the bullet in the 7TCU due to being concerned about expansion performance at lower velocities. However, in the Nosler manual, they recommend the Ballistic Tips in the 7TCU handgun. As I recall, they say the Ballistic Tips will perform down to 1700 or 1800 fps. Given that, I loaded the 140 gr BTs for hunting. So far, I have shot but one buck with it last fall in Texas, south of Uvalde. One shot at 70 yards, not a heavy buck, a broadside shot. Still, it blew right through. Buck ran 35 yards and dropped.
I'll tell you the biggest problem I had with it. I load 100 rounds at a time. So I brought my box to the deer camp. You would think 100 rounds would be enough for a deer hunt. My mistake was showing off my new rig to my buddies. Out in front of our camphouse is a hill with rocks all over. These guys with 7mags and whatnot started shooting my rifle at rocks. They couldn't believe how sweet this gun is to shoot. And, they were drilling these rocks ! They shot smaller and smaller rocks farther and farther away till I was down to 10 rounds. I was afraid I was going to run out of ammo ! So my advice is, whatever bullets you use, load up a bunch, cause your partners are going to want to shoot your gun.