If you know you will eventually reload, it is an EXCELLENT cartridge for whitetail and hogs.
I haven't seen anything made by Black Hills that would be considered "hot" loads in .45 Colt, but I have used Cor-Bon and Buffalo Bore. They are expensive. Also, be careful what gun you buy for use with hot .45 Colt loads. There might be others, but in a handgun I have only used Rugers and Ruger-based customs(Blackhawks and Blackhawk-size Vaqueros, Bisleys, Redhawks).
I started shooting handguns back in 2000 and chose a Ruger Blackhawk .45 Colt for my whitetail weapon at that time. I used the Buffalo Bore 260 Speer JSP (at maybe 1350fps) for a few hunts with great results while learning to reload. Now I use various loads for various .45 Colt Blackhawks, Vaqueros, new Vaqueros, and a Long Colt Hunter (5-shot Ruger) by Gary Reeder.
Low power loads are much easier to find than hot loads. Most gun shops I know of have cowboy and SAMMI spec loads which probably work alright on small game, but you can make your own much cheaper if you reload.
If it were me and I were to never reload, I would buy a .44 Magnum. Oh, but wait.....I have several of those also.