First, understand that the WFN should not have a nose length over .4, and especially with this weight and smaller. With this bullet, 1450 fps will be easy to get with H110 or 296 powder, but that will be far below maximum potential, or maximum safe pressure. In other words, this bullet will confine the powder better with the loads you'll be using, causing a better ignition and burn. This will be your best bullet if you want to shoot it with reduced velocities and especially if you want those loads to be accurate at long ranges, like 200 yards to as far as you can hit.
The WLN with .450 nose will probably have a slightly shorter bearing length than the above, but I'm not dead sure, as I'd have to look at the cut charts to be sure. However, velocity potential will be about the same, even with the heavier weight, because of maximized powder space. This bullet will definately shoot accurately at velocities down to 1000 fps, or even 800 fps, but only at shorter ranges, with instability occuring at increasinly shorter range as velocities are lowered. I don't recommend this bullet unless you want to shoot the 1000 fps loads only at close ranges, which could be as little as 50 yards but accuracy will probably hold up very well out to 100-150 yards. The variable will be how well your revolver is aligned, and set up dimensionally, if the barrel is lapped, etc. This bullet is designed for maximum power possible, and should really be ordered only if the primary desire is heavy loads.
For FA 454 use, the WLN with .4 nose and a weight of 340 gr. (more if desired) is perhaps the optimum heavy smasher.