That depends of what your trying to attain. Is accuracy and velocity where you want it?
Any of the powders mentioned here can be great for this caliber. 4895 is petty much a requirement if you like the shape of your op-rod in a grand. But if your in a bolt or SS you have more choices to try if accuracy isn't great.
Personally, 4350 has gotten me everything I could ask for from the 30-06. I only load the '06 with two bullets and even then the 180 takes the lions share of the room in my cartridge boxes. About 55-57grs of IMR 4350 is right in my guns. I like Hornady 180 RN, Sierra BTSP's as well as Nosler BT's for lighter stuff. Its a max load in some so be careful.
CW