I'd say yes, with the caveat that you use good strong bullets and be very careful with your shot placement. My wife killed a great big cow (6" taller than the 34" bull she was with) using her .257 Roberts and 120 grain Hornady Interlocks. It's all about where you put the bullet. I had good luck shooting mine with a 180 grain Partition from a .330 Win Mag, and a buddy of mine shot his with the same bullet from a .30-06. I wouldn't try to stretch the range too much with that .270 though...
Good luck with your hunt. They are amazing animals to hunt, plus they're darn tasty!