As Loyd says, the most accurate is the 250 LFN, but to get optimum killing power, I recommend a 220 gr WFN, loaded to produce a DV (displacement Velocity) of 100 minimum,125 maximum. At this DV, game up to moose will normally fold on the spot with chest hits. If you are good enough to shoot unwounded game at ranges beyond 150 yards, an LFN will be superior due to its better accuracy, but kill speed will be slower, though I've found that most game hit at ranges beyond 150 yards are not alarmed by the guns report, and don't try to run hard, so normally go down in short distinces. Normally, not always.