Kal52,
No problem taking a coyote at 25-50 yards if you are up to it. It depends on how good of a shot you are.
The problem I see is finding a SP101, 32 mag, with the 4" barrel. Ruger quit making the 4" version awhile back, and I hardly ever see a 4" for sale at the auction sites. I'm sure there are still some out there, but you'll probably have to pay a premium price for it.
Good luck in your search. I wouldn't mind having the 4" version, myself.
You might consider the 3" version. I have one and it shoots great. I wouldn't hesitate to shoot at a yote at 25-50 yards with it. A longer barrel doesn't necessarily make the gun more accurate. It gives you a better sight radius which helps make you more accurate.
And yes, the 32 Mag is also great for the gals. My wife claimed mine after shooting it. The first time we took it to the range, I brought 100 rounds for it. I got to shoot 6 rounds, the wife shot the other 94 rounds. She wouldn't give it back to me.
Skunk