There is no argument that 38/357 dies, brass, bullets, etc are cheap and easy to find. As stated before, you are only limited by case capacity, gun capacity and bullet weights available to you. I have several 357s from 2" barrels up to 10" barrels. All have their place and loads accordingly.
I also have 41 magnums that have full house loads and mild loads.
I also have 44 magnums that have full house loads and mild loads.
I also have 45 long colts that have full house loads and mild loads.
When I am out riding my quad and might run into a coyote, chuck, or other vermin, I take one of the 357s.
When I am traveling into and out of my deer hunting area where cats are not uncommon, I carry my 41 with a light load.
When I am traveling in areas with possibility of dangerous animals, I carry the 44 or 45.
Last year on a trip into northern panhandle of Idaho, I carried my 45LC with stout loads. In elk camp in WA, I carried my 44 mag.
With any of these guns, I can hit football size targets out to 75 yards with either left or right hand and a rest. If I use both hands offhand, I can do almost as well out to 100. It takes practice and knowledge of your handgun. I shoot several hundred rounds a month and have for many years.
So, you have to decide what you want the gun for, how much time and strength you have to practice, and your budget. If you are limited by budget, then the 38/357 and 45lc are your best bets. Brass, bullets, dies, etc are easy to find and inexpensive. If you don't mind spending a little more for brass and bullets, the 41s and 44 are mighty fine guns and you would be very happy with either.
Once you decide, load lots of mild loads, shoot with ear plugs AND ear muffs on, and shoot it lots. Shoot it while laying down and using a log for rest. Shoot it standing and leaning against a tree. Shoot it over the hood of your truck (but not thru the hood of the truck). Shoot at steel targets at your gun club. After you have shot several hundred rounds, load up something a little stouter. Go shoot it again. After about 500 rounds, you should have a mild load you like and should have worked your way up into a pretty stout load. If you pick any of the calibers listed above, I can give you proven loads and get you started. Once you are comfortable shooting the gun and have gained comfort and knowledge, then take off the ear muffs and shoot it a little more with only the ear plugs. Get used to the loader report without flinching. Only then will you be able to shoot it in a hunting situation without flinching from the report of the stout load.
Enjoy the gun of your choice and let us know how you are doing.
Steve
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