keep in mind with t/c's you get carbine like velocities that are formidable gains with standard pistol calibers. such as the 41, 44's, and 45's.
i dont know what it says about me, but i now lean towards calibers and velocities that get the job done, but with as little recoil and component use as possible. i like as many shots per pound as i can get. i would think a contender in 41, 44special or mag, 45 colt or acp with a nice cast bullet would be mild to shoot and lethal on game. i view the 460 and 500, 45-70 as gimmicks, more toys than anything else. but that is just me.