I would have to say yes to both questions...though some will tell you the chamber is too long on the .45/.410 to get good accuracy,my experience with a contender chambered in the same combo shows that it can be quite accurate anyway.
On the .308 my advice would be to stay away from the Wolf Brand ammo in any single shot,'cause the lacquer the factory seals the ammo with will melt,then cool and cause all kinds of extraction problems!