I agree with GB on the .22, but if you must have a center fire take a look at the various versions of the Makarov. I have several of them, and found all to be quality firearms. The Makarov is also a great choice for a mid-size defensive pistol. It is a semi-auto, small, and easy to carry, they are accurate and very dependable.
It shoots a (9x18) 9mm bullet, somewhat more powerful than the .380 cartridge, ammo is readily available, and surplus is reasonably priced. The Makarov is a very close copy of the German PPK. You should be able to purchase one for approximately $100-150. I am particularly partial to the Polish P-64 model, and like the Hungarian PA-63 with the alloy frame. The PA-63 is currently listed in the CDNN catalog at $99. if you purchase 3 or more, or for $109 if you buy one. If you know a dealer that will take care of the transfer, you can order, pay on your credit card, and have the gun delivered to the dealer. He may charge for the transfer, but that should not run more than $20.