H110 has never given me the accuracy that I am looking for in a hunting load... maybe if I was reeeeeeally careful with the scale to get everything perfect.... but I don't think I should work that hard for a powder. I do use it for protection loads though, raw horsepower, and the need to hit what is in front of me, 5 or 6" at 25 yards is plenty for that.
Unique has just given me a lot better accuracy. And for the plinkers, saves on powder. After a full day, unique will make even a dark blued gun look dirty, but it does the job well.
I was using 12.5 grns over a 200 grainer for a plinker load, and that is a nice feeling straight shooting round. 10 grains under a 300grn LFN makes a good hunting round.