Veral,
So weight does help, and is your preference over velocity.
Seems DV seems to play a big part. So power of a cartridge, is different than killing better, speed and reliability? Logic would be to preferably shoot a more controllable cartridge, so one can better place ones shots. Always thought caliber always gained a lot as you went bigger in diameter, but should have known from the past, that your WFN/WLN changes a lot of things. Just figured that if say a .50 cal is too light in weight, one would lose a lot of sectional density, resulting in a loss of penetration. But then again, what minimum penetration does one really need to break the shoulder of a charging grizzly? Again, doesn't it depend on caliber and its weight?
You stated for the .44, that you would be comfortable with a 280 WFN, but would prefer a 300 WFN or 320 WLN loaded to max.
Loaded to max you meant 125 DV?
For the .45 cal, what weight WFN would you be comfortable with, and what weight WFN and WLN would you recommend?
In using your DV formula, I multiply the DV I want X 4, then divide this answer by the meplat diameter. ie DV of 130 X 4=520, then divided by .380(.510"-.130" for a .510" LFN bullet) for a target velocity of 1368 fps, when I'm working out my loads.