maybe this will help.......
I'm not an expert either, but I've been shooting these things for a few years now. Redhawk, you want the patched portion of the bullet into the rifling, as far as possible to avoid damage to the patch upon firing. As others have said, a grease cookie is essential unless you plan on wiping after each shot.
Personally, when I load 500 gr PPBs, they are seated barely 1/16th" into the case - that way I can get all the powder i want behind them. These are strictly for target work though.
My hunting rounds are as follows : 420 gr .443" bullet, .100" cookie, .030 wad, then 75 grs Swiss 1.5, Winchester case, and a Fed 215 primer. About six breaths a shot on the tube and I can shoot all day. As mentioned in another post, the bullets are wiped with a little graphite after being inserted into the case.
As a rule of thumb, compress your powder enough to make room for the cookie.
I patch my bullets to .450( a snug fit in the muzzle ) and cast about 16:1.
Good shooting
t4t